Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225644 | 0.88 | AKT1 (0.37) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL7223815 | 0.86 | GAA (0.37) | MGAMGAASIMGAM2HSP90AA1 | |
| SCHEMBL7224843 | 0.85 | ACKR3 (0.40) | — | |
| SCHEMBL7072612 | 0.83 | RAB9A (0.49) | MGAMGAASIMGAM2HSP90AA1 | |
| SCHEMBL7224822 | 0.82 | CHRNA7 (0.47) | HSP90AA1L3MBTL1CHRNB2CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL7070829 | 0.82 | RAB9A (0.48) | MGAMGAASIMGAM2HSP90AA1 | |
| SCHEMBL7223699 | 0.82 | NPC1 (0.38) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL7224676 | 0.82 | SLC9A1 (0.45) | MGAMGAASIMGAM2SLC6A3 | |
| SCHEMBL7223707 | 0.81 | NPC1 (0.38) | MGAMGAASIMGAM2KDM1A | |
| SCHEMBL7232049 | 0.80 | MGAM (0.35) | MGAMGAASIMGAM2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |