Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225671 | 0.92 | RAB9A (0.38) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL7230667 | 0.88 | MGAM (0.35) | MAPTMAPK1KDM4ERAB9ANPC1 | |
| SCHEMBL7232049 | 0.86 | MGAM (0.35) | MAPTMAPK1KDM4ERAB9ANPC1 | |
| SCHEMBL7226764 | 0.85 | RAB9A (0.53) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL7224672 | 0.84 | S1PR4 (0.49) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL7223139 | 0.83 | NPC1 (0.42) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL7223699 | 0.82 | NPC1 (0.38) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL7224710 | 0.82 | GAA (0.45) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL7232072 | 0.82 | HTT (0.48) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL7231502 | 0.82 | CHRNB2 (0.46) | ALDH1A1MAPTMAPK1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |