Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL722492

CCCCCCCCCCCOCCCCCCCCCCC.N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.67
HTT P42858 2/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
MAPT P10636 1/20 0.67
CES2 O00748 2/20 0.54
TSHR P16473 2/20 0.53
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
USP2 O75604 1/20 0.50
CES1 P23141 1/20 0.48
LPAR3 Q9UBY5 3/20 0.44
LPAR1 Q92633 2/20 0.44
LPAR2 Q9HBW0 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2587274 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL715799 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL4438557 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL2587267 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL715250 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL2583073 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL6009607 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL715486 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL714199 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT
Ammonia Solution, Strong SCHEMBL27640240 1.00 THRB (0.67) THRBHTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130116120-A1 ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL N.V. (NL) 2013-05-09 US disclosed
US-8357636-B2 Alkoxylated alkylamines/alkyl ether amines with peaked distribution AKZO NOBEL N.V. (NL) 2013-01-22 US disclosed
EP-2032523-B1 PROCESS FOR PREPARATION OF ALKOXYLATED ALKYLAMINES / ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL NV (NL) 2012-06-20 EP disclosed
US-20120053054-A1 ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL N.V. (NL) 2012-03-01 US disclosed
US-8049039-B2 Process for preparation of alkoxylated alkylamines/alkyl ether amines with peaked distribution AKZO NOBEL N.V. (NL) 2011-11-01 US disclosed
US-8034979-B2 Reacting primary alkylamine with alkylene oxide in absence of any functional proportion of alkali catalyst to yield first intermediate followed by reacting intermediate with additional moles of alkylene oxide at temperature of 90-130 degrees C. in absence of alkali catalyst to yield ethoxylated product MONSANTO TECHNOLOGY LLC (US) 2011-10-11 US disclosed
US-20100056376-A1 ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION MONSANTO TECHNOLOGY LLC (US) 2010-03-04 US disclosed
US-20090209788-A1 PROCESS FOR PREPARATION OF ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL N.V. (NL) 2009-08-20 US disclosed
CN-101511175-A Alkoxylated alkylamines or alkoxylated alkyl ether amines with peaked distribution AKZO NOBEL NV (NL) 2009-08-19 CN disclosed
CN-101479232-A Process for preparation of alkoxylated alkylamines / alkyl ether amines with peaked distribution AKZO NOBEL NV (NL) 2009-07-08 CN disclosed
EP-2032523-A1 PROCESS FOR PREPARATION OF ALKOXYLATED ALKYLAMINES / ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION Akzo Nobel N.V. (NL) 2009-03-11 EP disclosed
WO-2007109791-A9 ALKOXYLATED ALKYLAMINES OR ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL NV (NL) 2009-01-15 WO disclosed
EP-2003965-A2 ALKOXYLATED ALKYLAMINES OR ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION Akzo Nobel N.V. (NL) 2008-12-24 EP disclosed
US-20080261814-A1 Alkoxylated Alkylamines/Alkyl Ether Amines With Peaked Distribution MONSANTO TECHNOLOGY LLC (US) 2008-10-23 US disclosed
WO-2007147866-A1 PROCESS FOR PREPARATION OF ALKOXYLATED ALKYLAMINES / ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL N.V. (NL) 2007-12-27 WO disclosed
CN-101080167-A Alkoxylated alkylamines / alkyl ether amines with peaked distribution AKZO NOBEL INC (NL) 2007-11-28 CN disclosed
WO-2007109791-A2 ALKOXYLATED ALKYLAMINES OR ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL N.V. (NL) 2007-09-27 WO disclosed
EP-1793667-A1 ALKOXYLATED ALKYLAMINES / ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION Akzo Nobel N.V. (NL) 2007-06-13 EP disclosed
WO-2006034459-A1 ALKOXYLATED ALKYLAMINES / ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION AKZO NOBEL N.V. (NL) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209788-A1 PROCESS FOR PREPARATION OF ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION ALKBH3, ALKBH2, ALKBH5 THRB 4617/4885HTT 1612/4885MEN1 1829/4885
US-20130116120-A1 ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION ALK, ALKBH3, NAT1 THRB 3906/4885HTT 688/4885MEN1 2271/4885
US-20100056376-A1 ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION ALK, ALKBH3, NAT1 THRB 3906/4885HTT 688/4885MEN1 2271/4885
US-20120053054-A1 ALKOXYLATED ALKYLAMINES/ALKYL ETHER AMINES WITH PEAKED DISTRIBUTION ALKBH3, ALKBH2, ALKBH1 THRB 4460/4885HTT 1421/4885MEN1 2669/4885
US-20080261814-A1 Alkoxylated Alkylamines/Alkyl Ether Amines With Peaked Distribution ALKBH3, ALKBH2, ALKBH1 THRB 4460/4885HTT 1421/4885MEN1 2669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.