Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217674 | 0.83 | HPGD (0.53) | POLBMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8055459 | 0.79 | KDM4E (0.42) | GAANPC1RAB9AKMT2A | |
| SCHEMBL20877679 | 0.73 | GPR3 (0.40) | — | |
| SCHEMBL20877639 | 0.73 | GPR3 (0.40) | — | |
| SCHEMBL2344909 | 0.73 | GAA (0.71) | GAAPLK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7217598 | 0.73 | HSP90AA1 (0.46) | NPC1RAB9A | |
| SCHEMBL8104116 | 0.73 | GAA (0.55) | GAAPLK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27291355 | 0.72 | HDAC6 (0.50) | PLK1EPHX2NR1H4RAB9A | |
| Dimethyl Sulfoxide SCHEMBL28063317 | 0.69 | GAA (0.82) | GAAPLK1POLBMEN1NPC1 | |
| SCHEMBL11062297 | 0.69 | ALDH1A1 (0.46) | POLBMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |