Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232527 | 0.92 | USP30 (0.42) | USP30NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7232579 | 0.90 | PTPN11 (0.43) | USP30SMN1; SMN2ALDH1A1FYNPTPN1 | |
| SCHEMBL7229786 | 0.88 | TYRO3 (0.42) | USP30KDM1AFYNP2RX7AAK1 | |
| SCHEMBL7230386 | 0.88 | USP30 (0.38) | USP30NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7224277 | 0.88 | USP30 (0.43) | USP30NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7230934 | 0.87 | KDM1A (0.43) | USP30NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7226302 | 0.86 | NPC1 (0.52) | USP30NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7224212 | 0.86 | USP30 (0.41) | USP30NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7225292 | 0.86 | P2RX7 (0.43) | USP30NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7223211 | 0.86 | USP30 (0.41) | USP30NPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |