Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.80 |
| ▸ | MMP9 | P14780 | 10/20 | 0.80 |
| ▸ | MMP3 | P08254 | 4/20 | 0.80 |
| ▸ | MMP13 | P45452 | 4/20 | 0.80 |
| ▸ | MMP1 | P03956 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230149 | 0.93 | MMP2 (0.70) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7229104 | 0.93 | MMP2 (0.79) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7230599 | 0.89 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7229708 | 0.82 | MMP2 (0.64) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL9219366 | 0.82 | MMP2 (0.55) | MMP2MMP9MMP3MMP13RAB9A | |
| SCHEMBL10674350 | 0.79 | RAB9A (0.82) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8483472 | 0.78 | RAB9A (0.74) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL10683303 | 0.77 | RAB9A (0.72) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6578080 | 0.77 | MMP2 (0.51) | MMP2MMP9MMP3MMP13RAB9A | |
| SCHEMBL10675533 | 0.77 | RAB9A (0.72) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605604-B1 | Tumour necrosis factor alpha release inhibitors; efficiency treatment of cancers, rheumatic diseases, arthritis, ulcers, atherosclerosis, asthma | LES LABORATOIRES SERVIER (FR) | 2003-08-12 | — | — | US | disclosed |