Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13864993 | 0.89 | BACE1 (0.50) | MAPTHSD17B10TUBB4ATUBBTUBA3C | |
| SCHEMBL7112160 | 0.82 | BACE1 (0.52) | MAPTHPGDHSD17B10TUBB4ATUBB | |
| SCHEMBL28751605 | 0.81 | TSHR (0.47) | HSD17B10TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7114628 | 0.81 | CYP3A4 (0.47) | MAPTHPGDHSD17B10BACE1TSHR | |
| SCHEMBL736176 | 0.79 | TUBB4A (0.63) | MAPTHPGDHSD17B10TUBB4ATUBB | |
| SCHEMBL8081555 | 0.79 | TDP1 (0.58) | MAPTHPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL14580012 | 0.78 | HPGD (0.44) | MAPTHPGDHSD17B10TPMTTSHR | |
| SCHEMBL14175572 | 0.78 | MAPT (0.43) | MAPTHPGDHSD17B10TUBB4ATUBB | |
| SCHEMBL919577 | 0.78 | ALDH1A1 (0.55) | MAPTHPGDBACE1ALOX5LMNA | |
| SCHEMBL3238033 | 0.78 | CYP4F2 (0.47) | MAPTHPGDTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |