Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707645 | 0.91 | LMNA (0.55) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL6194628 | 0.91 | CYP3A4 (0.55) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL16954598 | 0.89 | KMT2A (0.48) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL10765006 | 0.89 | KMT2A (0.44) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL7962269 | 0.89 | ABCB11 (0.45) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL16960587 | 0.89 | KMT2A (0.44) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL2010436 | 0.89 | LMNA (0.59) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL13725392 | 0.88 | RXRA (0.53) | ALDH1A1KMT2ALMNACYP3A4MEN1 | |
| SCHEMBL16533898 | 0.86 | CA1 (0.50) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL16960424 | 0.86 | TTR (0.54) | ALDH1A1KMT2ALMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| JP-10306009-A | — | — | None | — | — | JP | disclosed |
| JP-10306011-A | — | — | None | — | — | JP | disclosed |
| CN-116671398-A | Seedling breeding method for strong medicinal material cortex schizophragmatis integrifolii radicis | 广西白云山盈康药业有限公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20230266683-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2023-08-24 | — | — | US | disclosed |
| US-20230266684-A1 | IMAGE FORMING UNIT AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2023-08-24 | — | — | US | disclosed |
| CN-114630832-A | Pyrimido-cyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-3411036-B1 | 3,5-DISUBSTITUTED PYRAZOLES USEFUL AS CHECKPOINT KINASE 1 (CHK1) INHIBITORS, AND THEIR PREPARATIONS AND APPLICATIONS | PHARMAENGINE INC (TW) | 2021-12-29 | — | — | EP | disclosed |
| US-11116767-B2 | 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (Chk1) inhibitors, and their preparations and applications | PHARMAENGINE, INC. (TW) | 2021-09-14 | — | — | US | disclosed |
| US-20210137918-A1 | 3,5-DISUBSTITUTED PYRAZOLES USEFUL AS CHECKPOINT KINASE 1 (CHK1) INHIBITORS, AND THEIR PREPARATIONS AND APPLICATIONS | PHARMAENGINE, INC. (TW) | 2021-05-13 | — | — | US | disclosed |
| US-20030176498-A1 | Inhibitors of alpha4mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1315694-A2 | INHIBITORS OF ALPHA 4 MEDIATED CELL ADHESION | Tanabe Seiyaku Co., Ltd. (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-1300403-A1 | Process for the manufacture of hypoxyxylerone derivatives | Aventis Pharma S.A. (FR) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002018320-A2 | INHIBITORS OF α4 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |
| JP-H10306011-A | UNUNIFORMITY IMPROVING COSMETIC | POLA CHEM IND INC | 1998-11-17 | — | — | JP | disclosed |
| JP-H10306009-A | UNUNIFORMITY IMPROVING COSMETIC | POLA CHEM IND INC | 1998-11-17 | — | — | JP | disclosed |
| WO-1995011880-A1 | SUBSTITUTED AMIDES AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1995-05-04 | — | — | WO | disclosed |
| US-5399455-A | Electrophotographic toner composition and image fixing process | FUJI XEROX CO., LTD. (JP) | 1995-03-21 | — | — | US | disclosed |
| US-4749679-A | Heat sensitive recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-06-07 | — | — | US | disclosed |
| US-4644376-A | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137918-A1 | 3,5-DISUBSTITUTED PYRAZOLES USEFUL AS CHECKPOINT KINASE 1 (CHK1) INHIBITORS, AND THEIR PREPARATIONS AND APPLICATIONS | CHEK1, CHEK2, BUB1 | ALDH1A1 1679/4885KMT2A 1459/4885LMNA 1865/4885 |
| US-20030176498-A1 | Inhibitors of alpha4mediated cell adhesion | ITGB4, VCAM1, EPCAM | ALDH1A1 158/4885KMT2A 1616/4885LMNA 2495/4885 |
| US-11116767-B2 | 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (Chk1) inhibitors, and their preparations and applications | CHEK1, CHEK2, BUB1 | ALDH1A1 1679/4885KMT2A 1459/4885LMNA 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.