Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226161 | 0.95 | SLC6A3 (0.36) | SLC6A3SLC6A4SLC6A2HTR3EHTR3B | |
| SCHEMBL7225345 | 0.93 | CHRNA7 (0.41) | SLC6A3SLC6A4SLC6A2HTR3EHTR3B | |
| SCHEMBL7233475 | 0.90 | SLC6A3 (0.35) | SLC6A3SLC6A4SLC6A2HTR3EHTR3B | |
| SCHEMBL7225149 | 0.89 | HTR4 (0.37) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7223853 | 0.87 | CHRNA7 (0.43) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7231157 | 0.87 | SLC8A1 (0.33) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7232316 | 0.86 | NPC1 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7225471 | 0.86 | SLC6A3 (0.33) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7233882 | 0.86 | SLC6A3 (0.33) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7226014 | 0.85 | SLC6A2 (0.41) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |