Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229845 | 0.92 | SLC6A3 (0.42) | NPC1POLBRAB9ASLC6A4SLC6A3 | |
| SCHEMBL7233323 | 0.90 | ESR1 (0.37) | ALDH1A1HPGDSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7226014 | 0.90 | SLC6A2 (0.41) | HTR4NPC1ALDH1A1POLBRAB9A | |
| SCHEMBL7223301 | 0.90 | MAPT (0.36) | MAPTHPGDRAB9ASLC6A4 | |
| SCHEMBL7232095 | 0.89 | CHRNA7 (0.34) | ALDH1A1HPGDSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7225066 | 0.89 | SLC6A4 (0.41) | KDM4ESLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7226161 | 0.89 | SLC6A3 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7225381 | 0.89 | HTR3E (0.37) | NPC1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7226147 | 0.89 | SLC6A3 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7231735 | 0.88 | MMP2 (0.36) | SMN1; SMN2ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |