SCHEMBL7226192

SCHEMBL7226192

CCc1cccc2c1C1=C(C)C2[Zr]C2C(C)=C(c3c(CC)cccc32)[Si]1(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7188847 0.79 EDNRB (0.36)
SCHEMBL5359652 0.78 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL7186289 0.74
Chloromethane SCHEMBL7185377 0.72 PDCD1 (0.30)
SCHEMBL7194549 0.72 HSD11B1 (0.36)
SCHEMBL7191676 0.72
SCHEMBL7189475 0.68 EDNRB (0.36)
SCHEMBL7187131 0.68 EDNRB (0.31)
SCHEMBL7188934 0.67 EDNRB (0.30)
SCHEMBL18989345 0.65 HTR2B (0.51) GABRA1GABRB2HTR7HTR2BPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576306-B2 Of crystalline isotactic propylene polymer having 0.05 to 15 weight % comonomer units, broad, bimodal molecular weight distribution; made using at least two metallocenes in a sequential or parallel polymerization process EXXONMOBIL CHEMICAL PATENTS INC. 2003-06-10 US disclosed
US-20010039314-A1 Propylene polymers for films EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-08 US disclosed
EP-0897394-A1 USE OF HEAT TREATED ALUMOXANES IN PREPARING SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 1999-02-24 EP disclosed
WO-1997043320-A1 USE OF HEAT TREATED ALUMOXANES IN PREPARING SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 1997-11-20 WO disclosed