SCHEMBL722644

SCHEMBL722644

O=C(O)[C@H](O)C1=CCCC=C1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 1/20 0.31
PKM P14618 1/20 0.31
PTPN1 P18031 1/20 0.31
PTPN7 P35236 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
ESR2 Q92731 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722643 1.00 LMNA (0.35) LMNAMAPK1POLBPKMPTPN1
SCHEMBL14525328 1.00 LMNA (0.35) LMNAMAPK1POLBPKMPTPN1
SCHEMBL11567410 0.78 MEN1 (0.32) LMNAKMT2A
SCHEMBL14198755 0.78
SCHEMBL18901903 0.78 MEN1 (0.32) LMNAKMT2A
SCHEMBL10598027 0.77 NR1I2 (0.38) LMNABLM
SCHEMBL14138261 0.75
SCHEMBL18265835 0.72 CA1 (0.33)
SCHEMBL1977622 0.71
SCHEMBL22861792 0.71 HTR1E (0.36) LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539948-B Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2023-12-05 CN claimed
CN-113189214-B Large yellow croaker proliferation and releasing molecular marker and screening method thereof 宁波大学 2022-06-21 CN claimed
CN-114539948-A Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2022-05-27 CN claimed
CN-113189214-A Large yellow croaker proliferation and releasing molecular marker and screening method thereof based on liquid phase-tandem mass spectrometry technology 宁波大学 2021-07-30 CN claimed
CN-114539948-B Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2023-12-05 CN disclosed
CN-114539948-B Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2023-12-05 CN disclosed
US-11739345-B2 Methods of treating phenylketonuria BIOMARIN PHARMACEUTICAL INC. (US) 2023-08-29 US disclosed
CN-113189214-B Large yellow croaker proliferation and releasing molecular marker and screening method thereof 宁波大学 2022-06-21 CN disclosed
CN-112255335-B Plasma metabolism marker for distinguishing benign ovarian tumor from malignant ovarian tumor and application thereof 复旦大学 2022-06-17 CN disclosed
CN-114539948-A Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2022-05-27 CN disclosed
CN-114539948-A Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2022-05-27 CN disclosed
CN-113189214-A Large yellow croaker proliferation and releasing molecular marker and screening method thereof based on liquid phase-tandem mass spectrometry technology 宁波大学 2021-07-30 CN disclosed
CN-112255335-A Plasma metabolic marker for distinguishing benign ovarian tumor from malignant ovarian tumor and application thereof 复旦大学 2021-01-22 CN disclosed
WO-2019217513-A2 METHODS OF TREATING PHENYLKETONURIA BIOMARIN PHARMACEUTICAL INC. (US) 2019-11-14 WO disclosed
WO-2012027369-A2 SYSTEM AND METHOD FOR STRAIGHTENING OR SHAPING HAIR DIVERSAPACK OF CALIFORNIA, LLC (US) 2012-03-01 WO disclosed
EP-1016401-B1 Hair cleansing composition KAO CORP (JP) 2003-10-22 EP disclosed
US-6358502-B1 FOR LUSTER, SOFTNESS, BODY KAO CORPORATION (JP) 2002-03-19 US disclosed
US-6348189-B1 AND THE HYDROXY ACIDS, MALIC ACID AND MALEIC ACID; ANIONIC SURFACTANT SELECTED FROM AN ALKYLSULFURIC ACID SALT, AN ALKYLETHERSULFURIC ACID SALT, OR AN N-ALKYLAMIDO-ALKANOLSULFURIC ACID ESTER SALT; SHAMPOO KAO CORPORATION (JP) 2002-02-19 US disclosed
EP-1016401-A1 Hair cleansing composition Kao Corporation (JP) 2000-07-05 EP disclosed
EP-1016402-A2 Hair cosmetic composition Kao Corporation (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739345-B2 Methods of treating phenylketonuria PAH, PNMT, AADAT LMNA 2039/4885MAPK1 3887/4885POLB 1744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.