SCHEMBL722740

SCHEMBL722740

CC(C)(C)OC(=O)CCOCCOCCOCCOCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
STING1 Q86WV6 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TLR2 O60603 1/20 0.32
TLR1 Q15399 1/20 0.32
EPHX2 P34913 2/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31536455 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL225095 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL15444409 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL18383707 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL14706366 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL23274175 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL16283397 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40466 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL22771162 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL18356860 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
US-20250361249-A1 SURFACE TREATMENT AGENT DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
US-20250361250-A1 FLUORINE-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4644398-A1 SURFACE TREATMENT AGENT Daikin Industries, Ltd. (JP) 2025-11-05 EP disclosed
US-12448518-B2 Phthalocyanine dye compounds, conjugates and methods of use thereof Rakuten Medical, Inc. (US) 2025-10-21 US disclosed
EP-3538539-B1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-27 EP disclosed
US-12377159-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-08-05 US disclosed
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
US-20250215025-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 US disclosed
US-8426649-B2 Cyclopropenones and the photochemical generation of cyclic alkynes therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2013-04-23 US disclosed
WO-2012166560-A1 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACID LINKED DOLASTATIN DERIVATIVES AMBRX, INC. (US) 2012-12-06 WO disclosed
EP-1463558-B1 CYTOTOXIC AGENTS BEARING A REACTIVE POLYETHYLENE GLYCOL MOIETY, CYTOTOXIC CONJUGATES COMPRISING POLYETHYLENE GLYCOL LINKING GROUPS, AND METHODS OF MAKING AND USING THE SAME IMMUNOGEN INC (US) 2012-06-06 EP disclosed
US-20120053299-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-03-01 US disclosed
EP-1506181-A4 CYTOTOXIC AGENTS COMPRISING POLYETHYLENE GLYCOL-CONTAINING TAXANES AND THEIR THERAPEUTIC USE IMMUNOGEN INC (US) 2006-11-08 EP disclosed
EP-1506181-A1 CYTOTOXIC AGENTS COMPRISING POLYETHYLENE GLYCOL-CONTAINING TAXANES AND THEIR THERAPEUTIC USE Immunogen, Inc. (US) 2005-02-16 EP disclosed
US-6716821-B2 Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same IMMUNOGEN INC. 2004-04-06 US disclosed
US-20040001838-A1 CYTOTOXIC AGENTS BEARING A REACTIVE POLYETHYLENE GLYCOL MOIETY, CYTOTOXIC CONJUGATES COMPRISING POLYETHYLENE GLYCOL LINKING GROUPS, AND METHODS OF MAKING AND USING THE SAME IMMUNOGEN, INC. 2004-01-01 US disclosed
WO-2003097625-A1 CYTOTOXIC AGENTS COMPRISING POLYETHYLENE GLYCOL-CONTAINING TAXANES AND THEIR THERAPEUTIC USE IMMUNOGEN, INC. (US) 2003-11-27 WO disclosed
US-6596757-B1 Taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more polyethylene glycol-containing taxanes covalently bonded to a cell binding IMMUNOGEN INC. 2003-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215025-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND FLI1, AFF1, SF1 MEN1 473/4885KMT2A 897/4885TSHR 1265/4885
US-20120053299-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom WEE1, WEE2, MPI MEN1 3501/4885KMT2A 4486/4885TSHR 2381/4885
US-20250361250-A1 FLUORINE-CONTAINING SILANE COMPOUND FLI1, AFF1, RFT1 MEN1 216/4885KMT2A 663/4885TSHR 2035/4885
US-20040001838-A1 CYTOTOXIC AGENTS BEARING A REACTIVE POLYETHYLENE GLYCOL MOIETY, CYTOTOXIC CONJUGATES COMPRISING POLYETHYLENE GLYCOL LINKING GROUPS, AND METHODS OF MAKING AND USING THE SAME MCL1, CD47, BAX MEN1 2906/4885KMT2A 4468/4885TSHR 2602/4885
US-12377159-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 MEN1 2791/4885KMT2A 4548/4885TSHR 809/4885
US-20250361249-A1 SURFACE TREATMENT AGENT ITGA1, ITGB1, GDI1 MEN1 534/4885KMT2A 1052/4885TSHR 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.