SCHEMBL40466

SCHEMBL40466

CC(C)(C)OC(=O)CCOCCOCCOCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
STING1 Q86WV6 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TLR2 O60603 1/20 0.32
TLR1 Q15399 1/20 0.32
EPHX2 P34913 2/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31536455 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL225095 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL15444409 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL18383707 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL14706366 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL722740 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL23274175 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL16283397 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL22771162 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL18356860 1.00 MEN1 (0.44) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059939-B API synthesis method 南京恒远科技开发有限公司 2025-03-21 CN claimed
CN-119059939-A Synthesis method of Fmoc-NH-PEG4-CH2CH2CONbis (PEG 4-CH2CH2 COtBu) 南京恒远科技开发有限公司 2024-12-03 CN claimed
EP-4678240-A2 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES Hangzhou Dac Biotech Co., Ltd. (CN) 2026-01-14 EP disclosed
EP-3319936-B1 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES HANGZHOU DAC BIOTECH CO LTD (CN) 2025-12-17 EP disclosed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US disclosed
US-20250367188-A1 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC. (US) 2025-12-04 US disclosed
US-20250361249-A1 SURFACE TREATMENT AGENT DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
US-20250361250-A1 FLUORINE-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
EP-4644398-A1 SURFACE TREATMENT AGENT Daikin Industries, Ltd. (JP) 2025-11-05 EP disclosed
US-12448518-B2 Phthalocyanine dye compounds, conjugates and methods of use thereof Rakuten Medical, Inc. (US) 2025-10-21 US disclosed
US-20250302815-A1 PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS CALICO LIFE SCIENCES LLC 2025-10-02 US disclosed
WO-2008075152-A1 1- [4- (SULFONYL) -PHENYL] -5- (BENZYL) -IH-I, 2, 4-TRIAZOL DERIVATIVES AS INHIBITORS OF CARBONIC ANHYDRASE FOR TREATING GLAUCOMA OR OCULAR HYPERTENSION PFIZER PRODUCTS INC. (US) 2008-06-26 WO disclosed
WO-2008056346-A2 ANTI-ANGIOGENIC COMPOUNDS COVX TECHNOLOGIES IRELAND LIMITED (IE) 2008-05-15 WO disclosed
EP-1853294-A2 ANTI-ANGIOGENIC COMPOUNDS Covx Technologies Ireland Limited (IE) 2007-11-14 EP disclosed
WO-2007068718-A1 POLYPEPTIDE PROTRACTING TAGS NOVO NORDISK A/S (DK) 2007-06-21 WO disclosed
US-7141676-B1 Water soluble multi-biotin-containing compounds UNIVERSITY OF WASHINGTON (US) 2006-11-28 US disclosed
US-20060228325-A1 Water soluble multi-biotin-containing compounds WILBUR D S 2006-10-12 US disclosed
US-20060205670-A1 Conjugated to antibody; thrombospondin receptor targeting ZOETIS BELGIUM S.A. (BE) 2006-09-14 US disclosed
WO-2006094269-A2 ANTI-ANGIOGENIC COMPOUNDS COVX TECHNOLOGIES IRELAND LIMITED (IE) 2006-09-08 WO disclosed
WO-2004091542-A2 NITROGEN CONTAINING INTEGRIN TARGETING COMPOUNDS COVX PHARMACEUTICALS, INC. (US) 2004-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302815-A1 PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS PTPN1, PTPN2, PTPN18 MEN1 3882/4885KMT2A 1913/4885TSHR 538/4885
US-20060205670-A1 Conjugated to antibody; thrombospondin receptor targeting TEK, KDR, FLT4 MEN1 2043/4885KMT2A 3959/4885TSHR 382/4885
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM MEN1 2291/4885KMT2A 3090/4885TSHR 3166/4885
US-20060228325-A1 Water soluble multi-biotin-containing compounds BTD, HLCS, VNN1 MEN1 3462/4885KMT2A 4039/4885TSHR 3424/4885
US-20250361250-A1 FLUORINE-CONTAINING SILANE COMPOUND FLI1, AFF1, RFT1 MEN1 216/4885KMT2A 663/4885TSHR 2035/4885
US-20250361249-A1 SURFACE TREATMENT AGENT ITGA1, ITGB1, GDI1 MEN1 534/4885KMT2A 1052/4885TSHR 395/4885
US-20250367188-A1 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS SLC10A1, SLC10A2, FABP3 MEN1 4705/4885KMT2A 3647/4885TSHR 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.