Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | MAG | P20916 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822954 | 0.87 | TP53 (0.49) | POLBTP53MDM2MDM4HSP90AA1 | |
| SCHEMBL7233754 | 0.86 | L3MBTL1 (0.44) | POLBTP53MDM2LMNAKMT2A | |
| SCHEMBL965416 | 0.85 | TP53 (0.49) | POLBTP53MDM2MDM4HSP90AA1 | |
| SCHEMBL965417 | 0.85 | TP53 (0.49) | POLBTP53MDM2MDM4HSP90AA1 | |
| SCHEMBL7235898 | 0.84 | TYMP (0.45) | POLBKMT2ATYMP | |
| SCHEMBL7235905 | 0.84 | TYMP (0.45) | POLBKMT2ATYMP | |
| SCHEMBL7774713 | 0.84 | TP53 (0.47) | POLBTP53MDM2MDM4HSP90AA1 | |
| SCHEMBL16581497 | 0.84 | SSTR1 (0.43) | NT5ETACR1SSTR1SSTR2SSTR4 | |
| SCHEMBL7901248 | 0.84 | SSTR1 (0.43) | NT5ETACR1SSTR1SSTR2SSTR4 | |
| SCHEMBL9800967 | 0.83 | SSTR1 (0.42) | NT5ETACR1SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624190-B2 | Useful as biodegradable surfactants and in enzymatic processes using a chitinase (N-acetylglucosaminidase) | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 2003-09-23 | — | — | US | disclosed |
| US-20020028954-A1 | 2-acylamino-2-deoxy-glucono-1,5-lactones, a method for the production thereof, compositions containing them, and uses thereof | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028954-A1 | 2-acylamino-2-deoxy-glucono-1,5-lactones, a method for the production thereof, compositions containing them, and uses thereof | ENGASE, FUT5, CHIT1 | POLB 1945/4885TP53 4840/4885MDM2 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.