Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HRAS | P01112 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170361 | 0.91 | MAPK1 (0.50) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15516519 | 0.86 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL7227900 | 0.84 | POLB (0.43) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL7774709 | 0.84 | MAPK1 (0.50) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL16965886 | 0.82 | SSTR1 (0.40) | NT5ETACR2TNFTYMPSSTR4 | |
| SCHEMBL17435236 | 0.82 | HK1 (0.47) | MAPK1HRASTYMP | |
| SCHEMBL20608732 | 0.82 | HK1 (0.47) | MAPK1HRASTYMP | |
| SCHEMBL13491610 | 0.80 | MAPK1 (0.48) | TP53MDM2POLBL3MBTL1MAPK1 | |
| SCHEMBL10409434 | 0.80 | HTR1A (0.44) | NT5EBCHETACR2TYMPSSTR4 | |
| SCHEMBL10409432 | 0.80 | HTR1A (0.44) | NT5EBCHETACR2TYMPSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131311-A1 | 2-ACYLAMINO-2-DEOXY-GLUCONO-1,5-LACTONES, METHOD FOR OBTAINING SAME, COMPOSITIONS COMPRISING THEM AND USES | UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031059-A1 | 2-ACYLAMINO-2-DEOXY-GLUCONO-1,5-LACTONES, METHOD FOR OBTAINING SAME, COMPOSITIONS COMPRISING THEM AND USES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 2000-06-02 | — | — | WO | disclosed |