Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 12/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228038 | 1.00 | FABP4 (0.46) | FABP4ACLYHSD11B1FLT1FLT4 | |
| SCHEMBL7228039 | 1.00 | FABP4 (0.46) | FABP4ACLYHSD11B1FLT1FLT4 | |
| SCHEMBL14676834 | 0.81 | ACLY (0.48) | FABP4ACLYHSD11B1FLT1FLT4 | |
| SCHEMBL8022448 | 0.78 | MMP1 (0.51) | — | |
| SCHEMBL14676932 | 0.72 | PLG (0.43) | FABP4ACLYHSD11B1 | |
| SCHEMBL197058 | 0.67 | FABP4 (0.49) | FABP4ACLYFLT1FLT4KDR | |
| SCHEMBL14675686 | 0.67 | PGR (0.53) | HSD11B1FLT1FLT4KDR | |
| SCHEMBL2098095 | 0.67 | FLT1 (0.41) | FABP4ACLYFLT1FLT4KDR | |
| SCHEMBL9887819 | 0.66 | FLT1 (0.54) | FABP4ACLYFLT1FLT4KDR | |
| SCHEMBL6295818 | 0.66 | STS (0.48) | FABP4ACLYSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645939-B1 | Very late antigen-4 (VLA) integrin antagonists; antiallergens, antiasthmatics, and antiinflammatory agents; multiple sclerosis, autoimmune disease treatment | MERCK & CO., INC. | 2003-11-11 | — | — | US | disclosed |