Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235343 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNAUSP2MAPTSMN1; SMN2 | |
| SCHEMBL7235370 | 0.81 | CCR5 (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7239605 | 0.80 | PLAU (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2658182 | 0.80 | CCR5 (0.48) | ALDH1A1LMNAUSP2MAPTSMN1; SMN2 | |
| SCHEMBL2648987 | 0.75 | IDO1 (0.45) | ALDH1A1LMNAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7235286 | 0.74 | TACR1 (0.42) | ALDH1A1MAPTPRMT5GCGRGAA | |
| SCHEMBL7230499 | 0.74 | HPGD (0.51) | ALDH1A1LMNAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2650002 | 0.74 | IDO1 (0.37) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7228644 | 0.74 | IDO1 (0.55) | ALDH1A1LMNAMAPTHPGDALOX12 | |
| SCHEMBL7237910 | 0.74 | ABCB1 (0.49) | MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |