Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807405 | 0.80 | TDP1 (0.42) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL2807407 | 0.80 | TDP1 (0.42) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL1004802 | 0.76 | ATM (0.44) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL1004800 | 0.76 | ATM (0.44) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL8228620 | 0.75 | TDP1 (0.42) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL9685241 | 0.75 | TDP1 (0.42) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL10792060 | 0.75 | TDP1 (0.42) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL2807218 | 0.74 | ALOX15 (0.40) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL2807222 | 0.74 | ALOX15 (0.40) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL1006524 | 0.73 | AKR1C3 (0.48) | TDP1ATML3MBTL1ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528455-B1 | Post or preemergence herbicides such as 3-(4-chloro-2-fluoro -5-(1-methoxycarbonyl-1-vinyloxy)phenyl)-1-methyl-6-trifluoro methyl-2,4-pyrimidinedione | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |