Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231042 | 0.99 | MGLL (0.41) | MGLLKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7229971 | 0.90 | HCAR3 (0.45) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL7232819 | 0.89 | HCAR3 (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7240516 | 0.89 | HCAR3 (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7230456 | 0.83 | HCAR3 (0.42) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL7231715 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL7230151 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL7231034 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL7230965 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL7241764 | 0.78 | ALDH1A1 (0.44) | MGLLKDM4EALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509359-B1 | Use as a neuramninidase inhibitor in virus | BIOCRYST PHARMACEUTICALS, INC. | 2003-01-21 | — | — | US | disclosed |