Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.56 |
| ▸ | NOS2 | P35228 | 6/20 | 0.56 |
| ▸ | NOS3 | P29474 | 4/20 | 0.56 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743142 | 0.86 | NOS3 (0.56) | NOS1NOS2NOS3CCR1CCR5 | |
| SCHEMBL28737279 | 0.85 | NOS3 (0.54) | NOS1NOS2NOS3CCR1CCR5 | |
| SCHEMBL15709975 | 0.85 | NOS3 (0.54) | NOS1NOS2NOS3CCR1CCR5 | |
| SCHEMBL17115680 | 0.85 | KDM4E (0.44) | NOS1NOS2NOS3KDM4ENPSR1 | |
| SCHEMBL7229439 | 0.83 | POLB (0.54) | NOS1NOS2NOS3KDM4EMAPK1 | |
| SCHEMBL27037928 | 0.81 | NOS3 (0.50) | NOS1NOS2NOS3CCR1CCR5 | |
| SCHEMBL9814691 | 0.80 | NOS1 (0.53) | NOS1NOS2NOS3CCR1CCR5 | |
| SCHEMBL21450874 | 0.79 | NOS2 (0.56) | NOS1NOS2NOS3CCR1CCR5 | |
| SCHEMBL17801972 | 0.79 | NOS3 (0.51) | NOS1NOS2NOS3NPSR1MTNR1A | |
| SCHEMBL25199502 | 0.79 | WDR5 (0.48) | NOS1NOS2NOS3RIOK2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1666140-A | Polymer substrate for displays and light emitters | GEN ELECTRIC (US) | 2005-09-07 | — | — | CN | claimed |
| CN-1236410-C | Multi colour display device | UNIV PRINCETON (US) | 2006-01-11 | — | — | CN | disclosed |
| CN-1666140-A | Polymer substrate for displays and light emitters | GEN ELECTRIC (US) | 2005-09-07 | — | — | CN | disclosed |
| US-6521643-B1 | Prevention and/or treatment of nitric oxide synthasey medi-ated diseases such as adult respiratory distress syndrome, myocarditis, synovitis, septic shock, diabetes, ulcerative colitis, cerebral infarction, osteoarthritis | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| CN-1293425-A | Multi colour display device | UNIV PRINCETON (US) | 2001-05-02 | — | — | CN | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |