Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230379 | 0.98 | GAA (0.34) | GAAALDH1A1STAT6SMN1; SMN2 | |
| SCHEMBL7225316 | 0.87 | SIGMAR1 (0.36) | ALDH1A1STAT6SMN1; SMN2 | |
| SCHEMBL7224033 | 0.84 | KDM4E (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7229667 | 0.77 | GAA (0.32) | GAAALDH1A1SMN1; SMN2BIRC2 | |
| SCHEMBL7223828 | 0.76 | — | — | |
| SCHEMBL7228369 | 0.73 | ALDH1A1 (0.46) | GAAALDH1A1STAT6SMN1; SMN2 | |
| SCHEMBL7221817 | 0.71 | GAA (0.48) | GAAALDH1A1STAT6SMN1; SMN2 | |
| SCHEMBL7222432 | 0.71 | GAA (0.48) | GAAALDH1A1STAT6SMN1; SMN2 | |
| SCHEMBL7694509 | 0.71 | CHRM5 (0.44) | GAAALDH1A1STAT6SMN1; SMN2 | |
| SCHEMBL7222004 | 0.69 | SIGMAR1 (0.43) | GAAALDH1A1STAT6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552226-B1 | Rapid; low temperature; one pot synthesis; reduced catalytic quantities of such as lewis acid and tertiary amine; entiomerically pure products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | disclosed |
| WO-2002026683-A1 | TANDEM ACYL-CLAISEN REARRANGEMENT IN THE PREPARATION OF CHIRAL PRODUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-04 | — | — | WO | disclosed |