Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791741 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMAPTLMNA | |
| SCHEMBL9077666 | 0.83 | KMT2A (0.53) | KMT2AMAPTLMNAKDM4EMEN1 | |
| SCHEMBL6924446 | 0.82 | RAB9A (0.46) | ALDH1A1TDP1KMT2AMAPTLMNA | |
| SCHEMBL1276347 | 0.81 | KMT2A (0.58) | ALDH1A1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL11768896 | 0.81 | KMT2A (0.49) | ALDH1A1TDP1KMT2AMAPTLMNA | |
| SCHEMBL6398442 | 0.81 | THRB (0.55) | ALDH1A1TDP1KMT2AMAPTLMNA | |
| SCHEMBL3903145 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TDP1KMT2AMAPTLMNA | |
| SCHEMBL27968290 | 0.81 | PTPRC (0.41) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL72231 | 0.79 | MAPT (0.59) | ALDH1A1TDP1KMT2AMAPTLMNA | |
| SCHEMBL1883642 | 0.79 | KMT2A (0.47) | ALDH1A1TDP1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021224320-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2021-11-11 | — | — | WO | disclosed |
| WO-2012116237-A2 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE, LLC (US) | 2012-08-30 | — | — | WO | disclosed |
| US-6570029-B2 | Encapsulation of electronics | GEORGIA TECH RESEARCH CORP. | 2003-05-27 | — | — | US | disclosed |
| US-20020035201-A1 | No-flow reworkable epoxy underfills for flip-chip applications | GEORGIA TECH RESEARCH CORPORATION | 2002-03-21 | — | — | US | disclosed |
| WO-2001088959-A2 | NO-FLOW REWORKABLE EPOXY UNDERFILLS FOR FLIP-CHIP APPLICATIONS | GEORGIA TECH RESEARCH CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001072898-A1 | THERMALLY DEGRADABLE EPOXY UNDERFILLS FOR FLIP-CHIP APPLICATIONS | GEORGIA TECH RESEARCH CORPORATION (US) | 2001-10-04 | — | — | WO | disclosed |
| US-4310642-A | THERMOPLASTIC POLYMERS PREPARED FROM ETHYLENICALLY UNSATURATED MON | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4230548-A | CHAIN STOPPING WITH AN UNSATURATED DERIVATIVE OF AN ACYL CHLORIDE OR A CHLOROFORMATE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-28 | — | — | US | disclosed |
| US-4221645-A | Polycarbonates with end groups containing double bonds which can be crosslinked by UV light | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-09 | — | — | US | disclosed |