SCHEMBL723196

SCHEMBL723196

Nc1ccccc1CCCO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SIGMAR1 Q99720 2/20 0.42
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
FDPS P14324 1/20 0.40
ALOX15 P16050 2/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 2/20 0.38
TSHR P16473 1/20 0.37
CA2 P00918 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29573041 1.00 ALDH1A1 (0.43) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
Hydrochloric Acid SCHEMBL9992854 0.98 CYP3A4 (0.42) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL2857705 0.93 CYP3A4 (0.46) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL6931597 0.91 CYP3A4 (0.44) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL19429809 0.91 CYP3A4 (0.44) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
Carbamic Acid SCHEMBL28108896 0.90 SIGMAR1 (0.41) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
Nitric Acid SCHEMBL28557915 0.87 ALDH1A1 (0.37) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL249418 0.86 TDP1 (0.44) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL23159850 0.85 ALOX15 (0.47) ALDH1A1CYP3A4MAPTSIGMAR1FDPS
SCHEMBL23159894 0.85 ALOX15 (0.47) ALDH1A1CYP3A4MAPTSIGMAR1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117126896-A Method for preparing (R) -beta-amino alcohol by racemization removal through biological enzyme method 中山大学 2023-11-28 CN claimed
CN-113121265-B Intelligent release targeted migration type reinforcement corrosion inhibitor 江苏苏博特新材料股份有限公司 2022-11-22 CN claimed
CN-113880721-A Synthetic method of dapoxetine 湖南九典制药股份有限公司 2022-01-04 CN claimed
CN-113121265-A Intelligent release targeted migration type reinforcement corrosion inhibitor 江苏苏博特新材料股份有限公司 2021-07-16 CN claimed
CN-106458866-A Aminocarbonyl carbamate compound 爱思开生物制药株式会社 2017-02-22 CN claimed
CN-100404527-C Chiral 4,4'-dimethoxy-5,6,5',6'-bis methylene dioxy -2,2'-phthalic acid derivatives and process for preparing same QUALITY INSPECTION AND ANALYSI (CN) 2008-07-23 CN claimed
CN-100357256-C Method for synthesizing o-aminophenylpropyl alcohol UNIV SHANGHAI (CN) 2007-12-26 CN claimed
CN-1331835-C Preparation method of optically active beta-hydroxy ketone UNIV WUHAN (CN) 2007-08-15 CN claimed
EP-1497272-A4 METHOD OF PREPARING AMINE STEREOISOMERS APSINTERM LLC (US) 2007-02-07 EP claimed
CN-1837203-A Chiral 4,4'-dimethoxy-5,6,5',6'-bis methylene dioxy -2,2'-phthalic acid derivatives and process for preparing same QUALITY INSPECTION AND ANALYSI (CN) 2006-09-27 CN claimed
CN-1785950-A Preparation method of optically active beta-hydroxy ketone UNIV WUHAN (CN) 2006-06-14 CN claimed
CN-1760173-A Method for synthesizing o-aminophenylpropyl alcohol UNIV SHANGHAI (CN) 2006-04-19 CN claimed
EP-1497272-A2 METHOD OF PREPARING AMINE STEREOISOMERS Apsinterm, LLC. (US) 2005-01-19 EP claimed
WO-2003091207-A2 METHOD OF PREPARING AMINE STEREOISOMERS APSINTERM, LLC. (US) 2003-11-06 WO claimed
CN-1434048-A Chelating chiral boric acid ester and preparatio process and use thereof UNIV WUHAN (CN) 2003-08-06 CN claimed
CN-1241136-A Oxidation dye composition for keratin fibres OREAL (FR) 2000-01-12 CN claimed
CN-1241135-A Oxidation dyeing composition for keratin fibres OREAL (FR) 2000-01-12 CN claimed
CN-117165542-A Engineered beta-amino alcohol dehydrogenase and its use in chiral (R) -beta-amino alcohol preparation 中山大学 2023-12-05 CN disclosed
EP-0091594-A1 Aminocarboxylic acid derivatives Sanraku Incorporated (JP) 1983-10-19 EP disclosed
US-4226766-A ALKYL POLYPHOSPHATE, 2-AMINO-/2-HYDROXYETHYL/KETENIMINE OF BENZOPHENONE CRC COMPAGNIA DI RECERCA CHIMICA S.A. (CH) 1980-10-07 US disclosed