Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226687 | 0.90 | TUBB4A (0.46) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7226619 | 0.89 | HDAC1 (0.46) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7231176 | 0.89 | CA12 (0.39) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7222561 | 0.89 | CA12 (0.48) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7234526 | 0.89 | HDAC1 (0.47) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7224305 | 0.89 | HDAC1 (0.46) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7073214 | 0.89 | TUBB4A (0.47) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7230828 | 0.89 | SLC6A3 (0.41) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL7234556 | 0.88 | CA12 (0.44) | HDAC1HDAC6CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7072564 | 0.88 | TUBB4A (0.46) | HDAC1HDAC6CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |