Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.64 |
| ▸ | FABP4 | P15090 | 6/20 | 0.63 |
| ▸ | FABP3 | P05413 | 3/20 | 0.63 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.62 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15673372 | 0.88 | SIRT2 (0.77) | FTOFABP4FABP3FABP5SIRT2 | |
| SCHEMBL7238038 | 0.85 | MAPT (0.61) | FTOFABP4FABP3FABP5SIRT2 | |
| SCHEMBL10144151 | 0.85 | FABP4 (0.62) | FTOFABP4FABP3FABP5TAS2R14 | |
| Fenamic Acid SCHEMBL7265127 | 0.82 | FABP4 (0.77) | FTOFABP4FABP3FABP5TAS2R14 | |
| SCHEMBL4223666 | 0.81 | SIRT2 (0.61) | FABP4SIRT2SIRT1TAS2R14PTGS1 | |
| SCHEMBL7229231 | 0.81 | DHODH (0.64) | SIRT2PTGS1PTGS2MAPTMEN1 | |
| SCHEMBL28672317 | 0.80 | SIRT2 (0.61) | FABP4SIRT2SIRT1TAS2R14PTGS1 | |
| SCHEMBL25568703 | 0.80 | ALDH1A1 (0.47) | FTOFABP4FABP3FABP5SIRT2 | |
| SCHEMBL23868895 | 0.78 | ALDH1A1 (0.68) | SIRT2PTGS1PTGS2MAPTKDM4E | |
| SCHEMBL18271491 | 0.78 | ALDH1A1 (0.62) | SIRT2SIRT1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055263-A1 | Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-03-20 | — | — | US | disclosed |
| WO-2003006443-A2 | 2- 4-(NAPHTALIN-2-YL)-THIAZOL-2-YLAMINOCARBONYL BENZOIC ACID AND 2- 4-(NAPHTALIN-2-YL)-PYRIMIDIN-2-YLAMINOCARBONYL BENZOIC ACID AND ADDITIONAL COMPOUNDS SERVING AS TELOMERASE INHIBITORS FOR USE IN TUMOR THERAPY | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055263-A1 | Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production | TERT, POT1, REV1 | FTO 2546/4885FABP4 4393/4885FABP3 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.