Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389350 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C | |
| SCHEMBL723613 | 0.78 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL12848969 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C | |
| SCHEMBL4079752 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C | |
| SCHEMBL17378113 | 0.72 | GABRA1 (0.33) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C | |
| SCHEMBL9843757 | 0.71 | ALDH1A1 (0.33) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C | |
| Hydrogen Peroxide SCHEMBL10784213 | 0.71 | GABRA1 (0.58) | GABRA1GABRB2ALDH1A1ADRA2CHTR1A | |
| Hydrogen Peroxide SCHEMBL7819301 | 0.71 | GABRA1 (0.58) | GABRA1GABRB2ALDH1A1ADRA2CHTR1A | |
| SCHEMBL173300 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C | |
| SCHEMBL29763626 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423174-A1 | Reinforced ceramic micromechanical component | ETA SA Manufacture Horlogère Suisse (CH) | 2012-02-29 | — | — | EP | claimed |
| EP-2423174-A1 | Reinforced ceramic micromechanical component | ETA SA Manufacture Horlogère Suisse (CH) | 2012-02-29 | — | — | EP | disclosed |