Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812646 | 0.80 | MAP3K12 (0.43) | MAPK14JAK2JAK3 | |
| SCHEMBL19478461 | 0.80 | HTR7 (0.57) | HTR7PLK1ADRA1DHTR2CADRA1A | |
| SCHEMBL27305663 | 0.79 | AR (0.55) | ARHTR7ALDH1A1HPGDPLK1 | |
| SCHEMBL17439303 | 0.78 | HTR7 (0.56) | HTR7ADRA1DHTR2CADRA1AADRA1B | |
| SCHEMBL3555705 | 0.78 | HTR7 (0.59) | HTR7ADRA1DHTR2CADRA1AADRA1B | |
| SCHEMBL27709812 | 0.77 | AR (0.54) | ARHTR7ALDH1A1HPGDPLK1 | |
| SCHEMBL17372196 | 0.76 | MAP3K12 (0.41) | ARMAPK14JAK2JAK3 | |
| SCHEMBL30999000 | 0.76 | FDPS (0.41) | MAPK14 | |
| SCHEMBL5981398 | 0.75 | KDM4E (0.56) | HTR7ALDH1A1HPGD | |
| SCHEMBL17560828 | 0.75 | HTR7 (0.70) | ARHTR7PLK1EGFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055255-A1 | Synthesis of substituted imidazoles | MARCANTONIO KAREN (US) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055255-A1 | Synthesis of substituted imidazoles | KARS1, TKT, AADAC | AR 2987/4885HTR7 2547/4885ALDH1A1 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.