Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 2/20 | 0.57 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231334 | 0.90 | CASP6 (0.56) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7223574 | 0.90 | FGF1 (0.60) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7233377 | 0.90 | CASP6 (0.60) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7230646 | 0.89 | CASP6 (0.55) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7233109 | 0.89 | FGF1 (0.59) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7230621 | 0.89 | CASP6 (0.60) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL6240628 | 0.87 | CASP6 (0.72) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7230329 | 0.87 | CASP6 (0.57) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7224369 | 0.87 | CASP6 (0.57) | FGF1CASP6TIMP3MEN1KMT2A | |
| SCHEMBL7224470 | 0.86 | CD40 (0.59) | FGF1CASP6TIMP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653321-B1 | Stimulating kinase activity of insulin receptor; type II diabetes; hyperglycemia | TELIK, INC. | 2003-11-25 | — | — | US | disclosed |