Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32018464 | 1.00 | TERT (0.61) | TERTALOX5ALDH1A1GFERGAA | |
| SCHEMBL7600310 | 0.89 | MAPT (0.53) | TERTALOX5ALDH1A1GFERGAA | |
| SCHEMBL4229962 | 0.84 | TERT (0.63) | TERTALOX5ALDH1A1GAATDP1 | |
| SCHEMBL29557383 | 0.84 | ALDH1A1 (0.59) | TERTALOX5ALDH1A1GFERGAA | |
| SCHEMBL4213430 | 0.84 | ALDH1A1 (0.59) | TERTALOX5ALDH1A1GFERGAA | |
| SCHEMBL18010449 | 0.84 | KDM4E (0.65) | ALDH1A1GFERGAATDP1MAPT | |
| SCHEMBL161525 | 0.84 | KDM4E (0.65) | ALDH1A1GFERGAATDP1MAPT | |
| SCHEMBL30489955 | 0.84 | KDM4E (0.65) | ALDH1A1GFERGAATDP1MAPT | |
| SCHEMBL31411203 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GFERGAATDP1MAPT | |
| SCHEMBL31411201 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GFERGAATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805306-B1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORP (JP) | 2023-12-27 | — | — | EP | claimed |
| US-11708480-B2 | Rubber composition, tire, additive and hydrazide compound | OTSUKA CHEMICAL CO., LTD. (JP) | 2023-07-25 | — | — | US | claimed |
| CN-109563316-B | Rubber composition, tire, additive and hydrazide compound | 株式会社普利司通 | 2021-08-17 | — | — | CN | claimed |
| EP-3805306-A1 | RUBBER COMPOSITION AND TIRE | Bridgestone Corporation (JP) | 2021-04-14 | — | — | EP | claimed |
| EP-3495415-B1 | RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND | BRIDGESTONE CORP (JP) | 2021-01-20 | — | — | EP | claimed |
| WO-2019156093-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2019-08-15 | — | — | WO | claimed |
| WO-2019156094-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2019-08-15 | — | — | WO | claimed |
| EP-3515427-A2 | N-METHYL-D-ASPARTATE RECEPTOR ALLOSTERIC MODULATORS AND METHODS FOR THEIR USE | Qingdao Primedicine Pharmaceutical Co., Ltd (CN) | 2019-07-31 | — | — | EP | claimed |
| US-20190177513-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE | BRIDGESTONE CORPORATION (JP) | 2019-06-13 | — | — | US | claimed |
| EP-3495415-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND | Bridgestone Corporation (JP) | 2019-06-12 | — | — | EP | claimed |
| US-10202720-B2 | Flame resistant textile | MILLIKEN & COMPANY (US) | 2019-02-12 | — | — | US | claimed |
| US-9844610-B2 | Method for preparing in situ-formed hydrogel using enzyme-immobilized support, and biomedical use thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-12-19 | — | — | US | claimed |
| US-20150250890-A1 | METHOD FOR PREPARING IN SITU-FORMED HYDROGEL USING ENZYME-IMMOBILIZED SUPPORT, AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-09-10 | — | — | US | claimed |
| CN-102666969-B | Flame resistant textile | MILLIKEN & CO | 2015-07-01 | — | — | CN | claimed |
| US-8278820-B2 | Active matrix organic electroluminescent device and method of manufacture thereof | University of Electric Sience and Technology of China (CN) | 2012-10-02 | — | — | US | claimed |
| US-20110221331-A1 | Active matrix organic electroluminescent device and method of manufacture thereof | UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA | 2011-09-15 | — | — | US | claimed |
| WO-2011049700-A2 | FLAME RESISTANT TEXTILE | MILLIKEN & COMPANY (US) | 2011-04-28 | — | — | WO | claimed |
| US-20110092119-A1 | FLAME RESISTANT TEXTILE | MILLIKEN & COMPANY | 2011-04-21 | — | — | US | claimed |
| WO-2009026248-A2 | HYDRAZIDE, AMIDE, PHTHALIMIDE AND PHTHALHYDRAZIDE ANALOGS AS INHIBITORS OF RETROVIRAL INTEGRASE | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-02-26 | — | — | WO | claimed |
| WO-2002047455-A9 | FLUOROMETRIC CONTROL OF AROMATIC OXYGEN SCA VENGERS IN A BOILER SYSTEM | ONDEO NALCO CO (US) | 2002-09-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177513-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE | HRH2, HRH1, HEATR1 | TERT 17/4885ALOX5 606/4885ALDH1A1 277/4885 |
| US-11708480-B2 | Rubber composition, tire, additive and hydrazide compound | HRH2, HRH1, HEATR1 | TERT 13/4885ALOX5 617/4885ALDH1A1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.