Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 2/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235323 | 0.94 | KCNA3 (0.45) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7233534 | 0.94 | MTTP (0.45) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7238486 | 0.93 | HTR7 (0.43) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7243256 | 0.92 | HTR1A (0.42) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7238602 | 0.92 | HTR7 (0.43) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7570284 | 0.90 | SLC6A12 (0.47) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7235483 | 0.89 | HTR7 (0.43) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7234716 | 0.89 | HTR7 (0.49) | SLC6A12HTR1AHTR7CCR3HTR4 | |
| SCHEMBL7241197 | 0.89 | KCNA3 (0.45) | SLC6A12HTR1AHTR7CCR1CCR3 | |
| SCHEMBL7235931 | 0.88 | HTR7 (0.48) | HTR1AHTR7CCR3POLBKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617325-B1 | Inhibitors of the microsomal triglyceride-transfer protein | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-09 | — | — | US | disclosed |