Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232099 | 0.95 | MTTP (0.43) | HTR7HTR1APOLBCCR1CCR3 | |
| SCHEMBL7238486 | 0.94 | HTR7 (0.43) | HTR7HTR1ASLC6A12UBE2MDCUN1D1 | |
| SCHEMBL7234407 | 0.92 | SLC6A12 (0.44) | HTR7HTR1ASLC6A12POLBCCR1 | |
| SCHEMBL7235323 | 0.91 | KCNA3 (0.45) | HTR7HTR1ASLC6A12UBE2MDCUN1D1 | |
| SCHEMBL7238553 | 0.90 | HTR7 (0.43) | HTR7HTR1ASLC6A12UBE2MDCUN1D1 | |
| SCHEMBL7232909 | 0.90 | HTR7 (0.48) | HTR7HTR1APOLBCCR3HTR4 | |
| SCHEMBL7241958 | 0.89 | HTR7 (0.47) | HTR7HTR1APOLBCCR3KMT2A | |
| SCHEMBL7243256 | 0.89 | HTR1A (0.42) | HTR7HTR1ASLC6A12UBE2MDCUN1D1 | |
| SCHEMBL7235760 | 0.89 | HTR7 (0.45) | HTR7HTR1APOLBCCR1CCR3 | |
| SCHEMBL7235373 | 0.87 | MTTP (0.44) | HTR7HTR1APOLBCCR3KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617325-B1 | Inhibitors of the microsomal triglyceride-transfer protein | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-09 | — | — | US | disclosed |