Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239944 | 0.84 | ALDH1A1 (0.59) | CA2ALDH1A1GAALMNAKMT2A | |
| SCHEMBL3919692 | 0.81 | HDAC1 (0.51) | CA2ALDH1A1LMNAHDAC1HDAC2 | |
| SCHEMBL7241014 | 0.78 | ALDH1A1 (0.42) | CA2ALDH1A1GAALMNAKMT2A | |
| SCHEMBL9574391 | 0.77 | THRB (0.50) | CA2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9745362 | 0.77 | THRB (0.50) | CA2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20323522 | 0.74 | LOX (0.49) | ALDH1A1GAALMNAMEN1HTT | |
| SCHEMBL8234900 | 0.72 | CA2 (0.47) | CA2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9796132 | 0.71 | TNKS2 (0.42) | ALDH1A1LMNAHDAC1HDAC6PTGS2 | |
| SCHEMBL9555175 | 0.71 | TSHR (0.49) | CA2ALDH1A1GAALMNAMEN1 | |
| SCHEMBL9554912 | 0.71 | TSHR (0.49) | CA2ALDH1A1GAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6503998-B2 | Nonlinear Optical (nlo) materials, sulfon-diol-ether derivatives | NATIONAL SCIENCE COUNCIL (TW) | 2003-01-07 | — | — | US | disclosed |
| US-20020115869-A1 | Lambda-shaped carbazole and main-chain NLO polyurethane containing the same | NATIONAL SCIENCE COUNCIL (TW) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115869-A1 | Lambda-shaped carbazole and main-chain NLO polyurethane containing the same | POLL, POLK, LBR | CA2 3430/4885ALDH1A1 3259/4885GAA 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.