Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644965 | 0.84 | MAPK1 (0.59) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL5101721 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL3530917 | 0.82 | L3MBTL1 (0.49) | ALDH1A1HPGDHTTPOLBCYP2C19 | |
| SCHEMBL3150784 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL7055476 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL30168125 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL963475 | 0.82 | KDM4E (0.47) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL7209100 | 0.81 | HPGD (0.46) | ALDH1A1HPGDSMN1; SMN2HTTPOLB | |
| SCHEMBL1404979 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL6475322 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534496-B1 | Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0975624-A1 | THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046590-A1 | THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-22 | — | — | WO | disclosed |