Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587541 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL1836106 | 0.85 | L3MBTL1 (0.51) | HPGDALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL27693435 | 0.85 | SMN1; SMN2 (0.49) | HPGDALDH1A1ALOX15L3MBTL1KMT2A | |
| SCHEMBL29960499 | 0.84 | HPGD (0.56) | HPGDALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL2462870 | 0.84 | HPGD (0.56) | HPGDALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL5871517 | 0.83 | LMNA (0.48) | ALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL22323901 | 0.83 | L3MBTL1 (0.46) | HPGDALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL2463257 | 0.82 | HPGD (0.46) | HPGDALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL8173356 | 0.82 | ALDH1A1 (0.46) | HPGDALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL7236261 | 0.81 | ALDH1A1 (0.55) | HPGDALDH1A1LMNAHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| CN-106083722-A | A kind of Six Steps prepares the synthesis technique of pyrazoles Fluoxastrobin | 安徽广信农化股份有限公司 | 2016-11-09 | — | — | CN | disclosed |
| US-20120148521-A1 | Methods and Compositions for Controlled Release of Drugs | THE UNIVERSITY OF WYOMING | 2012-06-14 | — | — | US | disclosed |
| US-8105570-B2 | Covalently bond to polymer or other moiety that blocks activity until reaching delivery site; not easily circumventable | THE UNIVERSITY OF WYOMING (US) | 2012-01-31 | — | — | US | disclosed |
| EP-0987255-B1 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0735035-B1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6075148-A | CARBAMATE DERIVATIVES ARE USEFUL FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| EP-0987255-A2 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5981532-A | FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| US-5824705-A | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5714492-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0735035-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | HPGD 4800/4885ALDH1A1 1238/4885LMNA 2808/4885 |
| US-20120148521-A1 | Methods and Compositions for Controlled Release of Drugs | OPRK1, OPRM1, AANAT | HPGD 889/4885ALDH1A1 342/4885LMNA 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.