Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240048 | 0.89 | MAOA (0.67) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL7230998 | 0.83 | MAOA (0.58) | MAOAALDH1A1KDM4EABCB1ABCG2 | |
| SCHEMBL27918534 | 0.82 | MGAM (0.70) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL27714097 | 0.82 | MAOA (0.70) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL27876462 | 0.78 | MAOA (0.60) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL10127076 | 0.76 | MAOA (0.59) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL775094 | 0.75 | ABCG2 (0.60) | MAOAALDH1A1KDM4ENPC1ABCB1 | |
| SCHEMBL38655958 | 0.75 | MAOA (0.84) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL18240045 | 0.75 | MAOA (0.84) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL29365851 | 0.75 | MAOA (0.84) | MAOAALDH1A1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104936626-A | Coating for substrate | GORE & ASS | 2015-09-23 | — | — | CN | disclosed |
| CN-102526215-A | Extraction technology for removing polygala tenuifolia toxic substances and keeping anti-depressant effective components | LEI WANG | 2012-07-04 | — | — | CN | disclosed |
| US-6613797-B2 | New xanthone derivatives useful for treating protozoan diseases | INTERLAB, INC. | 2003-09-02 | — | — | US | disclosed |
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | disclosed |
| US-20020055644-A1 | Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins | INTERLAB, INC. | 2002-05-09 | — | — | US | disclosed |
| WO-2001041773-A1 | XANTHONE ANALOGS FOR TREATING INFECTIOUS DISEASES AND COMPLEXATION OF HEME AND PORPHYRINS | INTERLAB, INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| US-5977077-A | PARASITICIDES; ANTIPROTOZOA AGENT | INTERLAB CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055644-A1 | Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins | XPA, XDH, HMOX1 | MAOA 680/4885ALDH1A1 4117/4885KDM4E 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.