SCHEMBL775094

SCHEMBL775094

COc1cccc(-c2oc3c(OC)c(OC)c(OC)c(OC)c3c(=O)c2OC)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.60
ABCB1 P08183 3/20 0.60
KDM4E B2RXH2 4/20 0.49
MAPT P10636 3/20 0.49
GAA P10253 2/20 0.49
CYP3A4 P08684 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49
TUBB4A P04350 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48
TUBA4A P68366 1/20 0.48
TUBB4B P68371 1/20 0.48
TUBB3 Q13509 1/20 0.48
TUBB2A Q13885 1/20 0.48
TUBB8 Q3ZCM7 1/20 0.48
TUBA3E Q6PEY2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718719 0.90 ABCG2 (0.61) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL30049200 0.88 ABCG2 (0.56) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL5135083 0.87 ABCG2 (0.65) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL30998897 0.85 ABCB1 (0.52) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL15513876 0.83 ALDH1A1 (0.67) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL28646631 0.82 MAPT (0.63) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL29138747 0.81 KDM4E (0.53) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL28577776 0.80 KDM4E (0.62) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL27755056 0.77 KDM4E (0.58) ABCG2ABCB1KDM4EMAPTGAA
SCHEMBL29723654 0.77 KDM4E (0.59) ABCG2ABCB1KDM4EMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145581-A1 PURIFICATION PROCESS FOR POLYMETHOXYLATED FLAVONOIDS AND COMPOSITIONS OBTAINED THEREFROM FIRMENICH SA (CH) 2025-05-08 US claimed
US-20250032446-A1 METHODS AND COMPOSITIONS FOR THE BIOSYNTHESIS AND USE OF DEMETHYLATED POLYMETHOXY FLAVONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-01-30 US claimed
US-20240397987-A1 COMPOSITION DERIVED FROM CITRUS FRUIT AND BEVERAGE CONTAINING THE SAME SUNTORY HOLDINGS LIMITED (JP) 2024-12-05 US claimed
EP-4440334-A1 PURIFICATION PROCESS FOR POLYMETHOXYLATED FLAVONOIDS AND COMPOSITIONS OBTAINED THEREFROM Firmenich SA (CH) 2024-10-09 EP claimed
EP-4415560-A1 COMPOSITION DERIVED FROM CITRUS FRUIT AND BEVERAGE CONTAINING THE SAME Suntory Holdings Limited (JP) 2024-08-21 EP claimed
CN-118311172-A Quick identification method for shaddock variety 华南农业大学 2024-07-09 CN claimed
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 US claimed
CN-118102887-A Composition derived from citrus fruit and beverage containing the same 三得利控股株式会社 2024-05-28 CN claimed
US-20240090547-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-03-21 US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 US claimed
US-7108887-B2 Juice processing incorporating resin treatment TROPICANA PRODUCTS, INC. (US) 2006-09-19 US claimed
US-20060105089-A1 Byproduct from extracting citrus juice from whole fruit is made into a slurry and extracted to provide a rudimentary peel juice, processed into a raw peel juice and microfiltered to prepare a clarified raw peel juice; peel juice is processed to remove naturally occurring components, less bitter TROPICANA PRODUCTS, INC. 2006-05-18 US claimed
CN-1688212-A Juice processing incorporating resin treatment TROPICANA PROD INC (US) 2005-10-26 CN claimed
EP-1545246-A1 JUICE PROCESSING INCORPORATING RESIN TREATMENT TROPICANA PRODUCTS, INC. (US) 2005-06-29 EP claimed
US-20040152641-A1 Use of polymethoxylated flavones for treating insulin resistance KGK SYNERGIZE INC. (CA) 2004-08-05 US claimed
WO-2004021806-A1 JUICE PROCESSING INCORPORATING RESIN TREATMENT TROPICANA PRODUCTS, INC. (US) 2004-03-18 WO claimed
CN-1436528-A Anticancer medicine composition of citrus multimethoxy flavone and its prepn NANJING KAOYOU SCIENCE & TRADE (CN) 2003-08-20 CN claimed
US-20030064144-A1 Juice processing incorporating resin treatment TROPICANA PRODUCTS, INC. 2003-04-03 US claimed
WO-2002087567-A2 POLYMETHOXYLATED FLAVONES FOR TREATING INSULIN RESISTANCE KGK SYNERGIZE INC. (CA) 2002-11-07 WO claimed
EP-0233105-A1 Therapeutical compositions based on 3-alkoxyflavone derivatives and derivatives of 3-alkoxyflavones INSTITUT PASTEUR (FR) 1987-08-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032446-A1 METHODS AND COMPOSITIONS FOR THE BIOSYNTHESIS AND USE OF DEMETHYLATED POLYMETHOXY FLAVONES CYP51A1, CYP46A1, ERG28 ABCG2 2746/4885ABCB1 2853/4885KDM4E 81/4885
US-20250145581-A1 PURIFICATION PROCESS FOR POLYMETHOXYLATED FLAVONOIDS AND COMPOSITIONS OBTAINED THEREFROM TAS2R40, TAS2R60, TAS2R45 ABCG2 2402/4885ABCB1 4489/4885KDM4E 3790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.