SCHEMBL723639

SCHEMBL723639

CC(C)(C)OC(=O)NC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
DGAT1 O75907 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
BTK Q06187 1/20 0.39
CA12 O43570 2/20 0.37
CA14 Q9ULX7 2/20 0.37
APLNR P35414 1/20 0.37
CTSS P25774 2/20 0.37
CTSK P43235 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL28895816 0.97 MEN1 (0.41) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL101218 0.86 DGAT1 (0.46) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL15553702 0.84 MEN1 (0.37) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL15756433 0.84 GAA (0.40) MEN1GAAKMT2ADGAT1TDP1
Potassium SCHEMBL29554503 0.83 DGAT1 (0.44) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL6272856 0.83 DGAT1 (0.44) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL1522412 0.83 DGAT1 (0.44) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL27506147 0.82 MEN1 (0.41) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL14949475 0.81 DGAT1 (0.42) MEN1GAAKMT2ADGAT1TDP1
SCHEMBL12513316 0.80 KDM5B (0.46) MEN1GAAKMT2ADGAT1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2694524-B1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES US HEALTH (US) 2016-05-18 EP claimed
US-9284343-B2 2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-03-15 US claimed
EP-2820051-A1 DERIVATES BASED ON HYALURONIC ACID, CAPABLE OF FORMING HYDROGELS, METHOD OF PREPARATION THEREOF, HYDROGELS BASED ON SAID DERIVATIVES, METHOD OF PREPARATION THEREOF AND USE Contipro Biotech s.r.o. (CZ) 2015-01-07 EP claimed
US-20140051846-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES TheUnited ofAmerica,asrepresentedbythe Secre -tary,Department ofHealthand Human Service (US) 2014-02-20 US claimed
EP-2694524-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) 2014-02-12 EP claimed
WO-2013127374-A1 DERIVATES BASED ON HYALURONIC ACID, CAPABLE OF FORMING HYDROGELS, METHOD OF PREPARATION THEREOF, HYDROGELS BASED ON SAID DERIVATIVES, METHOD OF PREPARATION THEREOF AND USE CONTIPRO BIOTECH S.R.O. (CZ) 2013-09-06 WO claimed
WO-2012138530-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-10-11 WO claimed
EP-1248612-A4 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA INC (CA) 2005-09-07 EP claimed
EP-1248612-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA INC. (CA) 2002-10-16 EP claimed
WO-2001049288-A9 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA INC (CA) 2001-10-25 WO claimed
WO-2001049288-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA & CO. (CA) 2001-07-12 WO claimed
US-12636371-B2 Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system SKYBIO LLC (US) 2026-05-26 US disclosed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
EP-4652171-A1 TOTAL SYNTHESES OF PORTIMINE A AND ANALOGUES THEREOF AS SMALL MOLECULE MODULATORS OF NMD3 The Scripps Research Institute (US) 2025-11-26 EP disclosed
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease UNIVERSITE DE MONTREAL (CA) 2025-11-25 US disclosed
CN-1212705-A Serine protease inhibitors AKZO NOBEL NV (NL) 1999-03-31 CN disclosed
WO-1998015278-A1 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORPORATION (US) 1998-04-16 WO disclosed
WO-1998014192-A1 VITRONECTIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1998-04-09 WO disclosed
WO-1997047194-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 1997-12-18 WO disclosed
WO-1997031939-A1 SERINE PROTEASE INHIBITORS AKZO NOBEL N.V. (NL) 1997-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, DPYD MEN1 1888/4885GAA 2625/4885KMT2A 2305/4885
US-12636371-B2 Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system SLC6A2, SLC6A3, SLC18A2 MEN1 2497/4885GAA 605/4885KMT2A 2876/4885
US-20140051846-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES NSUN2, RNGTT, RNMT MEN1 1919/4885GAA 3844/4885KMT2A 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.