Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331965 | 0.80 | MAOA (0.52) | MAOAMAOBSLC6A4TAAR1SLC6A2 | |
| SCHEMBL7362590 | 0.80 | MAOA (0.52) | MAOAMAOBSLC6A4TAAR1SLC6A2 | |
| SCHEMBL7245397 | 0.77 | ADRB2 (0.46) | SLC6A4SLC6A2SLC6A3CYP2A6SMN1; SMN2 | |
| SCHEMBL7242681 | 0.77 | MEN1 (0.42) | SMN1; SMN2MAPTLMNACYP2D6ALDH1A1 | |
| SCHEMBL7243544 | 0.77 | EPHX1 (0.57) | SLC6A4SLC6A2SLC6A3CYP2A6SMN1; SMN2 | |
| SCHEMBL7240946 | 0.76 | ALDH1A1 (0.35) | MAOAMAOBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10344557 | 0.75 | MAOA (0.41) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL24012949 | 0.75 | MAOA (0.41) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL7246793 | 0.74 | LMNA (0.41) | SLC6A4SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL343269 | 0.74 | SMN1; SMN2 (0.45) | MAOAMAOBSLC6A4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639109-B1 | Reacting amino alcohol with sulfuric acid then reacting resulting amino sulfate with a mercaptan; simple, safe, rapid | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1216988-A1 | THIOALKYLAMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |