⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490833 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL20395920 | 0.81 | — | — | |
| SCHEMBL301679 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL560373 | 0.76 | — | — | |
| SCHEMBL252711 | 0.70 | — | — | |
| Carbimide SCHEMBL3149105 | 0.68 | KDM4E (0.30) | — | |
| Propane SCHEMBL28183675 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL4362792 | 0.67 | CYP1A2 (0.38) | — | |
| Alcohol SCHEMBL20856433 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL6689112 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106163531-B | Use of composition comprising surface-modified chondrocyte-derived extracellular matrix membrane as active ingredient for preventing adhesion | 亚洲大学校产学协力团 | 2019-12-13 | — | — | CN | claimed |
| US-11913030-B2 | Method of preparing mimicking angiogenic co-spheroids and application thereof | NATIONAL TAIWAN UNIVERSITY (TW) | 2024-02-27 | — | — | US | disclosed |
| CN-112154153-A | Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use | 百时美施贵宝公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-111094341-A | Antibodies having functional domains in the elbow region between the variable and constant domains | 生物医学研究院 | 2020-05-01 | — | — | CN | disclosed |
| US-20200071678-A1 | METHOD OF PREPARING MIMICKING ANGIOGENIC CO-SPHEROIDS AND APPLICATION THEREOF | NATIONAL TAIWAN UNIVERSITY (TW) | 2020-03-05 | — | — | US | disclosed |
| US-10449269-B2 | Particle conjugated prosthetic patches and methods of making and using thereof | YALE UNIVERSITY (US) | 2019-10-22 | — | — | US | disclosed |
| US-20180055972-A1 | PARTICLE CONJUGATED PROSTHETIC PATCHES AND METHODS OF MAKING AND USING THEREOF | YALE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| WO-2011014257-A9 | APPROACHES TO TREAT CANCER USING HB-EGF INHIBITORS SUCH AS MYRSINOIC ACID A | THE GENERAL HOSPITAL CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011014257-A1 | APPROACHES TO TREAT CANCER USING HB-EGF INHIBITORS SUCH AS MYRSINOIC ACID A | THE GENERAL HOSPITAL CORPORATION (US) | 2011-02-03 | — | — | WO | disclosed |
| WO-2009132032-A2 | SONIC HEDGEHOG MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-10-29 | — | — | WO | disclosed |
| CN-1244803-A | Soluble CTLA4 mutant molecules and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | CN | disclosed |