Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395932 | 0.83 | KMT2A (0.38) | HPGDKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6961808 | 0.79 | HSD17B10 (0.43) | DDR1NPSR1HPGDKMT2AMEN1 | |
| SCHEMBL7239319 | 0.78 | HCAR1 (0.53) | NPSR1HPGDKMT2AALDH1A1MCOLN3 | |
| SCHEMBL6970185 | 0.78 | F2 (0.43) | DDR1NPSR1HPGDKMT2AMEN1 | |
| SCHEMBL6975927 | 0.76 | HSD17B10 (0.41) | DDR1NPSR1HPGDKMT2AMEN1 | |
| SCHEMBL1188720 | 0.75 | TPMT (0.61) | DDR1HPGDFFAR2KDM4E | |
| SCHEMBL1188363 | 0.75 | LMNA (0.47) | DDR1HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL986399 | 0.75 | HPGD (0.44) | DDR1HPGDPOLBFFAR2KDM4E | |
| SCHEMBL30251625 | 0.75 | TPMT (0.61) | DDR1HPGDFFAR2KDM4E | |
| SCHEMBL12989210 | 0.75 | CES2 (0.61) | KMT2AMEN1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670381-B2 | (pyridin-4-ylamino)-alkoxy)-benzamide derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-12-30 | — | — | US | disclosed |
| US-20020169189-A1 | Benzamide derivatives as thrombin inhibitors | KELLY HENRY ANDERSON (GB) | 2002-11-14 | — | — | US | disclosed |
| US-6441008-B1 | ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION | 2002-08-27 | — | — | US | disclosed |
| EP-1117644-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020394-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169189-A1 | Benzamide derivatives as thrombin inhibitors | TFPI, TFPI2, F3 | DDR1 1301/4885NPSR1 1416/4885HPGD 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.