Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | QDPR | P09417 | 1/20 | 0.55 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239508 | 1.00 | LSS (0.73) | LSSDRD2POLBQDPRSLC18A3 | |
| SCHEMBL23442954 | 0.93 | LSS (0.65) | LSSDRD2POLBQDPRSLC18A3 | |
| SCHEMBL8082343 | 0.88 | LSS (0.60) | LSSDRD2SRD5A1SLC6A3 | |
| SCHEMBL23134213 | 0.88 | LSS (0.60) | LSSDRD2SRD5A1SLC6A3 | |
| SCHEMBL16963377 | 0.83 | DRD2 (0.61) | LSSDRD2SLC18A3SRD5A1MEN1 | |
| SCHEMBL10265387 | 0.81 | DRD2 (0.59) | LSSDRD2SLC18A3SRD5A1MEN1 | |
| SCHEMBL81500 | 0.81 | QDPR (0.56) | LSSDRD2QDPRSLC18A3 | |
| SCHEMBL10169266 | 0.80 | QDPR (0.51) | LSSDRD2QDPR | |
| SCHEMBL315186 | 0.79 | HTR3A (0.58) | LSSDRD2POLBSLC18A3SRD5A1 | |
| SCHEMBL24092733 | 0.79 | QDPR (0.55) | LSSDRD2QDPRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605621-B1 | Safe and effective detoxification after treating drug addiction, or diseases wherein cocaine is administered | GEORGETOWN UNIVERSITY | 2003-08-12 | — | — | US | disclosed |