SCHEMBL7239728

SCHEMBL7239728

CC=Cc1ccc(Oc2ccc(CCC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
KDM4E B2RXH2 1/20 0.52
THRB P10828 2/20 0.45
PTPN1 P18031 1/20 0.44
ACACB O00763 1/20 0.41
ACACA Q13085 1/20 0.41
RAB9A P51151 1/20 0.41
RELA Q04206 1/20 0.38
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
FFAR1 O14842 1/20 0.36
AHR P35869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7239725 1.00 ALDH1A1 (0.52) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL10415171 0.88 ALDH1A1 (0.46) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL10415170 0.88 ALDH1A1 (0.46) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL7232016 0.86 ALDH1A1 (0.45) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL7232012 0.86 ALDH1A1 (0.45) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL7240421 0.86 THRB (0.42) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL7240417 0.86 THRB (0.42) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL7229478 0.84 TNNC1 (0.42) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL7229479 0.84 TNNC1 (0.42) ALDH1A1LMNATP53CYP3A4TSHR
SCHEMBL21110872 0.84 LMNA (0.70) ALDH1A1LMNATP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed