SCHEMBL723985

SCHEMBL723985

c1ccc(C(OB(OC(c2ccccc2)(c2ccccc2)c2ccccc2)OC(c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.43
MAPK1 P28482 1/20 0.40
KCNN4 O15554 4/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.37
CYP2C19 P33261 2/20 0.33
HIF1A Q16665 1/20 0.33
CYP1A2 P05177 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
PTPN1 P18031 1/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
ESR2 Q92731 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723986 0.79 KIF11 (0.40) KIF11MAPK1KCNN4ALDH1A1TSHR
SCHEMBL28419769 0.79 KIF11 (0.40) KIF11MAPK1KCNN4ALDH1A1TSHR
SCHEMBL1333548 0.79 TSHR (0.42) KIF11MAPK1KCNN4ALDH1A1TSHR
SCHEMBL1333551 0.75 ALDH1A1 (0.39) KIF11MAPK1KCNN4ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL2816571 0.75 KIF11 (0.38) KIF11MAPK1KCNN4ALDH1A1TSHR
SCHEMBL22206118 0.74 HTR2A (0.47) ALDH1A1HIF1AESR1CYP3A4
SCHEMBL9004518 0.74 ALDH1A1 (0.37) KIF11MAPK1KCNN4ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL9347147 0.74 ALDH1A1 (0.37) KIF11MAPK1KCNN4ALDH1A1TSHR
SCHEMBL723306 0.74 ALDH1A1 (0.37) KIF11MAPK1KCNN4ALDH1A1TSHR
SCHEMBL8973 0.73 KIF11 (0.48) KIF11MAPK1KCNN4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827775-B2 Ethylene-cyclic mono olefin copolymerizations NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2023-11-28 US claimed
US-20220306792-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE CORNELL UNIVERSITY 2022-09-29 US claimed
EP-4028432-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE Cornell University (US) 2022-07-20 EP claimed
WO-2022123414-A1 LOW CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2022-06-16 WO claimed
US-20220119628-A1 ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2022-04-21 US claimed
US-11066493-B2 Catalyst injection system for an olefin polymerization reactor NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2021-07-20 US claimed
WO-2021051103-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE CORNELL UNIVERSITY (US) 2021-03-18 WO claimed
WO-2020079552-A1 ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2020-04-23 WO claimed
US-20200066993-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-27 US claimed
US-20200055969-A1 CATALYST INJECTION SYSTEM FOR AN OLEFIN POLYMERIZATION REACTOR NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2020-02-20 US claimed
US-20080177020-A1 tridentate ligands bonded to metals, suitable as catalysts in the preparation of olefin polymers CALIFORNIA INSTITUTE OF TECHNOLOGY 2008-07-24 US claimed
WO-2008036882-A1 NON-METALLOCENE ORGANOMETALLIC COMPLEXES AND RELATED METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2008-03-27 WO claimed
US-6777509-B2 POLYETHYLENE; BROAD MOLECULAR WEIGHT DISTRIBUTION NOVA CHEMICALS (INTERNATIONAL) S.A (CH) 2004-08-17 US claimed
US-20030004288-A1 Solution polymerization process NOVA CHEMICALS (INTERNATIONAL) S.A. 2003-01-02 US claimed
WO-2002092649-A2 SOLUTION POLYMERIZATION PROCESS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2002-11-21 WO claimed
JP-H09506135-A 1997-06-17 JP claimed
EP-0732972-A4 CATALYST FOR USE IN OLEFIN POLYMERIZATION OR COPOLYMERIZATION MOBIL OIL CORP (US) 1997-06-11 EP claimed
EP-0732972-A1 CATALYST FOR USE IN OLEFIN POLYMERIZATION OR COPOLYMERIZATION MOBIL OIL CORPORATION (US) 1996-09-25 EP claimed
US-5498582-A ZIRCONIUM OR HAFNIUM COMPOUND WITH CYCLOPENTADIENE WITH ANION AND SUPPORT FOR POLYMERIZATION MOBIL OIL CORPORATION (US) 1996-03-12 US claimed
WO-1995015815-A1 CATALYST FOR USE IN OLEFIN POLYMERIZATION OR COPOLYMERIZATION MOBIL OIL CORPORATION (US) 1995-06-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177020-A1 tridentate ligands bonded to metals, suitable as catalysts in the preparation of olefin polymers TPR, POF1B, OSTC KIF11 1622/4885MAPK1 3471/4885KCNN4 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.