Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10809959 | 0.84 | MMP2 (0.53) | MMP2MMP8MMP14MMP1CYP2C9 | |
| SCHEMBL9639793 | 0.78 | MMP2 (0.47) | MMP2MMP8MMP14MMP1CYP2C9 | |
| SCHEMBL10867968 | 0.78 | NR1H2 (0.48) | MMP2MMP8MMP14HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL10808794 | 0.77 | MMP2 (0.47) | MMP2MMP8MMP14MMP1CYP2C9 | |
| SCHEMBL5847584 | 0.76 | LMNA (0.50) | MMP2MMP8MAPTNPSR1CA12 | |
| 1,4-Dichlorobenzene SCHEMBL28425304 | 0.76 | LMNA (0.57) | MMP2MMP8MMP14MMP1MAPT | |
| SCHEMBL108542 | 0.75 | KCNH2 (0.47) | MMP2CYP2C9CYP2C19HSD17B10MAPT | |
| SCHEMBL11764837 | 0.74 | MMP2 (0.49) | MMP2MMP8MMP14MMP1CYP2C9 | |
| Hydrochloric Acid SCHEMBL4656192 | 0.73 | KCNH2 (0.45) | MMP2CYP2C9CYP2C19HSD17B10MAPT | |
| SCHEMBL6831542 | 0.73 | ACP3 (0.48) | MMP2MMP8MMP14MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231492-C | Solution phase synthesis of oligonucleotides | EFSSIA LTD (GB) | 2005-12-14 | — | — | CN | disclosed |
| US-6506894-B1 | Phosphonation; oxidation in situ with sulfur transfer agent | AVECIA LIMITED (GB) | 2003-01-14 | — | — | US | disclosed |
| CN-1274361-A | Solution phase synthesis of oligonucleotides | EFSSIA LTD (GB) | 2000-11-22 | — | — | CN | disclosed |