Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.49 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20362192 | 0.80 | KCNH3 (0.54) | KCNH3LMNASMN1; SMN2MAPK1TDP1 | |
| SCHEMBL2937099 | 0.80 | KCNH3 (0.54) | KCNH3LMNASMN1; SMN2MAPK1TDP1 | |
| SCHEMBL27484229 | 0.78 | KCNH3 (0.52) | KCNH3LMNASMN1; SMN2CDK7TDP1 | |
| SCHEMBL17604111 | 0.77 | HTT (0.47) | CDK2CCNA2CDK5DYRK1ACDK5R1 | |
| SCHEMBL6671578 | 0.77 | FYN (0.52) | CDK2CCNA2CDK5DYRK1ACDK5R1 | |
| SCHEMBL459453 | 0.77 | FYN (0.52) | CDK2CCNA2CDK5DYRK1ACDK5R1 | |
| SCHEMBL5424944 | 0.77 | CCNT1 (0.50) | CDK2CCNA2CDK5DYRK1ACDK5R1 | |
| SCHEMBL5359412 | 0.77 | CCNT1 (0.50) | CDK2CCNA2CDK5DYRK1ACDK5R1 | |
| SCHEMBL7241204 | 0.76 | ALDH1A1 (0.45) | CDK2CCNA2CDK5DYRK1ACDK5R1 | |
| SCHEMBL7241211 | 0.76 | ALDH1A1 (0.45) | CDK2CCNA2CDK5DYRK1ACDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670381-B2 | (pyridin-4-ylamino)-alkoxy)-benzamide derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-12-30 | — | — | US | disclosed |
| US-20020169189-A1 | Benzamide derivatives as thrombin inhibitors | KELLY HENRY ANDERSON (GB) | 2002-11-14 | — | — | US | disclosed |
| US-6441008-B1 | ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION | 2002-08-27 | — | — | US | disclosed |
| EP-1117644-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020394-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169189-A1 | Benzamide derivatives as thrombin inhibitors | TFPI, TFPI2, F3 | LATS1 4546/4885LATS2 4621/4885CDK2 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.