Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244783 | 0.85 | POLB (0.55) | KMT2AMEN1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL7251023 | 0.79 | LMNA (0.46) | KMT2AMEN1UBE2NTDP1GAA | |
| SCHEMBL4994825 | 0.78 | KMT2A (0.56) | KMT2AMEN1UBE2NTDP1CYP2C9 | |
| SCHEMBL7244603 | 0.77 | SIRT2 (0.44) | KMT2AMEN1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL6306501 | 0.76 | KMT2A (0.67) | KMT2AMEN1UBE2NTDP1CYP2C9 | |
| SCHEMBL7839981 | 0.75 | FAAH (0.49) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL7248765 | 0.75 | HTT (0.50) | KMT2AMEN1TDP1GAANPSR1 | |
| SCHEMBL7242765 | 0.75 | GSK3A (0.49) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7247950 | 0.74 | ADRA2A (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7248746 | 0.73 | GSK3A (0.51) | TDP1SMN1; SMN2ALDH1A1ALDH3A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632811-B2 | Administering cycloalkyl, lactam, lactone compounds for for inhibiting beta -amyloid peptide release and/or its synthesis in a cell | ATHENA NEUROSCIENCES, INC. | 2003-10-14 | — | — | US | disclosed |