SCHEMBL724327

SCHEMBL724327

N#CC(=O)c1cc[c]cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.31
GABRG2 P18507 3/20 0.31
GABRB3 P28472 3/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL750508 0.78 ALDH1A1 (0.50)
SCHEMBL441463 0.76 MAPK1 (0.33)
SCHEMBL1712905 0.76 KMT2A (0.41)
SCHEMBL4000363 0.74 CES2 (0.58)
SCHEMBL4322089 0.72 MAPK1 (0.32)
SCHEMBL1713036 0.72 ALDH1A1 (0.46)
SCHEMBL1266916 0.72 SMN1; SMN2 (0.40)
SCHEMBL1712644 0.72 ABL1 (0.42)
Methyl Alcohol SCHEMBL28939417 0.71 CES2 (0.54)
SCHEMBL5666673 0.71 TSHR (0.59) GABRA1GABRG2GABRB3GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118079019-A Mitochondrial thermosensitive release nano preparation, preparation method and application thereof in preparation of deep tumor therapeutic drugs 浙江中医药大学 2024-05-28 CN claimed
US-20240043529-A1 METHODS AND COMPOSITIONS RELATED TO BCL2 AND BIM HETERODIMER ANTIBODIES EUTROPICS PHARMACEUTICALS INC (US) 2024-02-08 US claimed
US-20230330058-A1 SENOLYTIC COMPOUNDS AND COMPOSITIONS Nuchido Limited (GB) 2023-10-19 US claimed
WO-2023139263-A1 PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX UNIVERSITE D'AIX-MARSEILLE (FR) 2023-07-27 WO claimed
EP-4210656-A1 SENOLYTIC COMPOUNDS AND COMPOSITIONS Nuchido Limited (GB) 2023-07-19 EP claimed
CN-112899328-B Method for synthesizing adenosine triphosphate by using yeast whole cell catalysis 南京同凯兆业生物技术有限责任公司 2023-06-02 CN claimed
WO-2023010004-A1 METHODS AND COMPOSITIONS RELATED TO MCL-1 AND BIM HETERODIMER ANTIBODIES CARDONE MICHAEL H (US) 2023-02-02 WO claimed
WO-2022140556-A1 METHODS AND COMPOSITIONS RELATED TO BCL2 AND BIM HETERODIMER ANTIBODIES EUTROPICS PHARMACEUTICALS, INC. (US) 2022-06-30 WO claimed
WO-2022053800-A1 SENOLYTIC COMPOUNDS AND COMPOSITIONS Nuchido Limited (GB) 2022-03-17 WO claimed
CN-112899328-A Method for catalytically synthesizing adenosine triphosphate by using yeast whole cell 南京同凯兆业生物技术有限责任公司 2021-06-04 CN claimed
WO-2013170176-A2 SURROGATE FUNCTIONAL DIAGNOSTICS TEST FOR CANCER EUTROPICS PHARMACEUTICALS, INC. (US) 2013-11-14 WO claimed
US-20130096086-A1 MITOCHONDRIA AND HUMAN IMMUNODEFIENCY VIRUS TYPE 1 NEW YORK UNIVERSITY 2013-04-18 US claimed
EP-2368112-A1 LIVER CELL TOXICITY ASSAY Corning Inc. (US) 2011-09-28 EP claimed
WO-2010065372-A1 LIVER CELL TOXICITY ASSAY CORNING INCORPORATED (US) 2010-06-10 WO claimed
US-20100129854-A1 LIVER CELL TOXICITY ASSAY CORNING INCORPORATED 2010-05-27 US claimed
EP-1104484-B1 COMPOSITION AND METHODS FOR EXPOSING ANTIGENIC EPITOPES ON CULTURED MICROORGANISMS BIOCONTROL SYSTEMS INC (US) 2008-10-15 EP claimed
US-20020127699-A1 Composition, formulae, devices and methods for control of specificity and inclusivity of microorganisms containing closely related antigen epitopes BIOCONTROL SYSTEMS, INC. (US) 2002-09-12 US claimed
EP-1104484-A2 COMPOSITION AND METHODS FOR EXPOSING ANTIGENIC EPITOPES ON CULTURED MICROORGANISMS BioControl Systems, Inc. (US) 2001-06-06 EP claimed
CN-1254382-A Bioluminescent reporter bacterium and methods for toxicity monitoring in biological wastewater treatment systems EASTMAN CHEM CO (US) 2000-05-24 CN claimed
WO-2000010013-A2 COMPOSITION AND METHODS FOR EXPOSING ANTIGENIC EPITOPES ON CULTERED MICROORGANISM BIOCONTROL SYSTEMS, INC. (US) 2000-02-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096086-A1 MITOCHONDRIA AND HUMAN IMMUNODEFIENCY VIRUS TYPE 1 MAVS, MT-CO1, CYC1 GABRA1 3749/4885GABRG2 4152/4885GABRB3 3879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.