SCHEMBL7244191

SCHEMBL7244191

CCCCOC(=O)Nc1ncnc(N(C(=O)OC)C(=O)OC)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.45
NPC1 O15118 5/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
CASP1 P29466 1/20 0.45
L3MBTL1 Q9Y468 4/20 0.44
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPK1 P28482 2/20 0.42
MAPT P10636 1/20 0.42
MCL1 Q07820 1/20 0.42
EGFR P00533 2/20 0.41
KDR P35968 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
GAA P10253 1/20 0.41
CSNK2A2 P19784 1/20 0.41
CSNK2A1 P68400 1/20 0.41
NFKB1 P19838 1/20 0.40
STAT1 P42224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7243752 0.90 RAB9A (0.40) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL6256084 0.83 RAB9A (0.52) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL6270005 0.79 RAB9A (0.51) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL6578768 0.79 RAB9A (0.51) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL996720 0.76 L3MBTL1 (0.55) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL7238236 0.76 LMNA (0.51) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL994563 0.73 RAB9A (0.55) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL7806424 0.73 RAB9A (0.51) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL2906397 0.72 RAB9A (0.51) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1
SCHEMBL2903601 0.72 RAB9A (0.51) RAB9ANPC1SMN1; SMN2CASP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506898-B1 Halogen-free, purity; curing agents CYTEC TECHNOLOGY CORP. 2003-01-14 US disclosed
EP-0624577-B1 Process for the preparation of 1,3,5-triazine carbamates, at least biscarbamate functional 1,3,5-triazines CYTEC TECH CORP (US) 2001-09-19 EP disclosed
US-6288226-B1 CURING CARBONATES CYTEC TECHNOLOGY CORPORATION 2001-09-11 US disclosed
US-6063922-A Carbamate functional 1,3,5-triazines CYTEC TECHNOLOGY CORP. (US) 2000-05-16 US disclosed
EP-0976739-A2 A Process for the preparation of 1,3,5-triazine carbamates, at least biscarbimate functional 1,3,5-triazines as well as use of 1,3,5-triazine carbamates CYTEC TECHNOLOGY CORP. (US) 2000-02-02 EP disclosed
US-5792866-A Process for the preparation of 1,3,5-triazine carbamates from amino 1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORPORATION (US) 1998-08-11 US disclosed
US-5705641-A Process for the preparation of 1,3,5-triazine carbamates from amino-1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORP. (US) 1998-01-06 US disclosed
EP-0624577-A1 Process for the preparation of 1,3,5-triazine carbamates, at least biscarbamate functional 1,3,5-triazines and their use as crosslinkers CYTEC TECHNOLOGY CORP. (US) 1994-11-17 EP disclosed