Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092382 | 0.74 | ITK (0.31) | — | |
| SCHEMBL7242736 | 0.74 | CLK1 (0.36) | KDM4EMAPT | |
| SCHEMBL7237712 | 0.60 | RAD52 (0.36) | — | |
| SCHEMBL7232820 | 0.58 | ALDH1A1 (0.39) | KDM4EMAPT | |
| SCHEMBL7630028 | 0.58 | ABCB1 (0.36) | MAPTHTT | |
| SCHEMBL7707552 | 0.58 | LTB4R (0.31) | CACNA1B | |
| SCHEMBL16055915 | 0.57 | KDM4E (0.51) | KDM4EMAPTALOX12HTT | |
| SCHEMBL17131831 | 0.54 | MAPT (1.00) | KDM4EMAPTALOX12HTT | |
| SCHEMBL30855012 | 0.54 | MAPT (0.89) | KDM4EMAPTALOX12HTT | |
| SCHEMBL20129089 | 0.54 | LSS (0.34) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627647-B1 | Substituted 1-(4-aminophenyl)imidazoles and their use as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-09-30 | — | — | US | claimed |
| WO-2001070703-A2 | SUBSTITUTED 1-(4-AMINOPHENYL)IMIDAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-09-27 | — | — | WO | claimed |